Whenever you are considering breaking something up, bands or otherwise, I think it’s good to try and imagine explaining your reasons to someone (kids, fans) ten years later. Does it sound petty? Would you be embarrassed recounting it? Then it’s probably a dumb reason to break up.
Jessica Hopper has been giving really good advice to musicians in this Fan Landers column recently, but this strikes me as the best advice yet, especially in an era in which almost no one can remain broken-up forever.